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Non-routine testing of patients with suspected COVID-19 of little benefit to assess risk

Non-routine testing of patients with suspected COVID-19 to help predict their prognosis on admission to emergency departments offers limited benefit and could have significant cost implications, according to a collaborative evaluation by Cardiff University and the University Hospital of Wales. Researchers drew together laboratory and clinical findings at Wales’s largest hospital from the first wave […]

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Dual checkpoint blockade promising as pre-surgical approach for certain patients with localized bladder cancer

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center. […]

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Teens diagnosed with depression show reduction in educational achievement

Teenagers who receive a depression diagnosis during their school career show a substantial decline in attainment in Year 11, new King’s College London research has found. The researchers suggest that targeted educational support for children struggling with depression might particularly benefit boys and those from deprived backgrounds, who were especially vulnerable subgroups in this study, […]

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Fighting intestinal infections with the body’s own endocannabinoids

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows. The findings, published online today in Cell, could help explain why the cannabis plant—the most potent […]

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Neurologic Manifestations Seen in Most Hospitalized With COVID-19

WEDNESDAY, Oct. 7, 2020 — Neurologic manifestations are common in COVID-19, occurring in 82.3 percent of hospitalized patients, according to a study published online Oct. 5 in the Annals of Clinical and Translational Neurology. Eric M. Liotta, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues characterized neurologic manifestations, their risk […]