A US Food and Drug Administration (FDA) advisory panel has endorsed a pancreatic islet cell transplant therapy for the treatment of people with type 1 diabetes that can’t be managed with current therapies. On April 15, the FDA’s Cellular, Tissue, and Gene Therapies Advisory Committee voted 12 to 4 in favor of approval of donislecel […]
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Personalized Cancer Vaccine Shows Early Promise Across Tumor Types
A personalized genomic cancer vaccine proved feasible to manufacture and was well tolerated in a phase 1 trial, according to researchers. The vaccine, PGV-001, was given to 13 patients with solid tumors or multiple myeloma who had a high risk of recurrence after surgery or autologous stem cell transplant. At last follow-up, four patients were […]
UK: Lockdown, Not Vaccines, Behind Drop in COVID Deaths
LONDON (Reuters) – British Prime Minister Boris Johnson warned on Tuesday that the rapid drop in COVID-19 deaths was largely down to a three-month lockdown, not the vaccination programme, and that cases would rise once again as restrictions ease. The United Kingdom launched its inoculation drive in December and has already offered a first shot […]
Manufacturing workers more susceptible for developing carpal tunnel syndrome
Researchers at Henry Ford Health System have found that workers in construction and other manufacturing jobs are more susceptible for developing carpal tunnel syndrome than those who work in office jobs. In a retrospective study published in the Journal of Occupational and Environmental Medicine, researchers report that manual labor jobs that require lifting, gripping and […]
Cannabis use disorder linked to increased complications after spinal surgery
For patients undergoing spinal surgery, the diagnosis of cannabis use disorder is associated with higher complication rates, including substantially increased risks of stroke and respiratory complications, reports a study in Spine. “Chronic cannabis use among patients undergoing spine surgery is associated with higher rates of inpatient neurovascular, thromboembolic, and pulmonary complications, and less favorable overall […]
Bedside Video Oculography-Based Test Tracks Loss of Otolith Function
NEW YORK (Reuters Health) – A novel bedside test using video oculography detected and tracked loss of otolith function in a case-control study. “Recent advances in video oculography have made it possible to measure vestibulo-ocular function at the bedside,” Dr. Amir Kheradmand of Johns Hopkins University School of Medicine in Baltimore told Reuters Health by […]
‘Like a War Zone’: One Nephrologist’s COVID-19 Experience
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. This past January, cases of COVID-19 spiked in Orange County, California, leaving hospitals scrambling to obtain enough continuous renal replacement therapy (CRRT) and dialysis machines. “Nearly half of our regular hospital beds had been converted into ICU beds, and we had […]
Could a cast be as good as surgery for treating wrist fracture for older people?
Wrist fractures are one of the most common fracture types. The burden of injury and costs of wrist fractures globally are substantial, with surgical treatment the popular treatment choice without strong supporting evidence. The CROSSFIRE study has shown that surgical treatment for wrist fracture (volar-locking plates) does not offer clinical advantages in pain and function […]
COVID-19 Virus Reinfections Rare, but Riskiest After Age 65
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The first large study of its kind reveals that SARS-CoV-2 reinfections remain rare, although people older than 65 are at higher risk. When researchers analyzed test results of 4 million people who had been infected with COVID-19 in Denmark, they found […]
Bypass surgery turned doctor from couch potato into mountain climber
Because of the lack of oxygen at such lofty altitudes, Dr. Akil Taherbhai needed four hours to climb the last mile to the peak of Mount Kilimanjaro, the highest freestanding mountain in the world. Savoring the sense of triumph as he finally reached the summit, the family physician who is known as Dr. Taher to […]