Health News

Therapeutic-dose anticoagulation benefits moderately ill COVID-19 patients

Moderately ill patients hospitalized with COVID-19 have better chances of survival if treated with therapeutic-dose anticoagulation, according to an international study involving 121 sites, including UT Southwestern Medical Center. Moderately ill COVID-19 patients treated with therapeutic-dose anticoagulation with unfractionated or low molecular-weight heparin were 27% less likely to need cardiovascular respiratory organ support such as […]

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New transparent material can capture respiratory droplets effectively from air

Although plexiglass barriers are seemingly everywhere these days — between grocery store lanes, around restaurant tables and towering above office cubicles — they are an imperfect solution to blocking virus transmission. Instead of capturing virus-laden respiratory droplets and aerosols, plexiglass dividers merely deflect droplets, causing them to bounce away but remain in the air. To […]

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Can fingerprick blood tests help evaluate antibody response and longevity against SARS-CoV-2 post-vaccination?

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread globally. To date, over 142.1 million cases have been confirmed worldwide. Vaccination rollouts have commenced in most countries in an attempt to arrest the spread of SARS-CoV-2. Antibody testing can help determine the magnitude of the pandemic […]

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Small molecule inhibitors of SARS-CoV-2 identified by screening

Even as the vaccine rollout continues against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seeking to bring an end to the coronavirus disease 2019 (COVID-19) pandemic, new variants emerge that show immune escape capabilities. Effective and safe drugs thus remain essential to treat severe infections with this virus. A new preprint, released on the […]

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Novel polyclonal antibody XAV-19 efficiently neutralizes UK and South African SARS-CoV-2 variants

A promising new study, released as a preprint on the bioRxiv* server, reports on the high neutralizing efficacy of a polyclonal swine antibody against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the novel coronavirus disease 2019 (COVID-19). By demonstrating the ability of this antibody to neutralize all currently circulating viral […]

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Glycans influence SARS-CoV-2 spike–ACE2 binding affinity, finds study

A study conducted at the Los Alamos National Laboratory, USA, and Concordia University, Canada, has explored the impact of different types of glycans on the interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and human angiotensin-converting enzyme 2 (ACE2) receptor. The findings reveal that although the spike – ACE2 interaction is not […]

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Researchers offer large-scale screening of potential broad-spectrum SARS-CoV-2 antivirals

The search for effective and safe antivirals against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen responsible for the current coronavirus disease 2019 (COVID-19) pandemic assumes new urgency in the face of more virulent and transmissible variants. Apart from the development of new drugs, the repurposing of already approved drugs has been a promising […]