Health News

Link between driver of ovarian cancer and metabolism opens up new therapeutic strategies

Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online in Nature Cancer. Researchers also showed that pharmacologic inhibition of glutamine metabolism may represent an effective therapeutic strategy for ARID1A-mutant ovarian cancer. […]

Health News

An epidemic of overdiagnosis: Melanoma diagnoses skyrocket

In a Sounding Board article published in The New England Journal of Medicine, H. Gilbert Welch MD, MPH, Senior Investigator, Center for Surgery and Public Health, Brigham and Women’s Hospital and colleagues present evidence for why they believe that increased diagnostic scrutiny is the primary driver of the rapid rise in melanoma diagnoses. Melanoma of […]