Health News

Studies reveal mutations that boost blood stem cell growth and increase leukemia and heart disease risk

As people grow older, certain genetic mutations in hematopoietic stem cells (HSCs)—which give rise to blood and immune cells—can eventually cause cancer or predispose people to cardiovascular disease. Now, two teams of scientists at the Broad Institute of MIT and Harvard, Massachusetts General Hospital, Boston Children’s Hospital, and Dana-Farber Cancer Institute have each discovered a […]

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A new map catalogs the effects of coronavirus mutations

As the novel coronavirus spreads, it’s picking up new mutations—for better and for worse. Now, Howard Hughes Medical Institute Investigator Jesse Bloom and his colleagues have cataloged how nearly 4,000 different mutations alter SARS-CoV-2’s ability to bind to human cells. Their data, publicly available online as an interactive map, is a new resource for researchers […]

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Artificial intelligence finds patterns of mutations and survival in tumour images

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI), the Wellcome Sanger Institute, Addenbrooke’s Hospital in Cambridge, UK, and collaborators have developed an artificial intelligence (AI) algorithm that uses computer vision to analyze tissue samples from cancer patients. They have shown that the algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns of […]

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Rare, damaging inherited mutations work together to reduce lifespan

Scientists report that the combined effects of rare, damaging mutations present at birth have a negative impact on healthspan and longevity, according to a study published this week in eLife. The findings suggest one additional inherited damaging mutation could carve off six months of life, and combinations of these rare mutations determine how soon someone […]