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The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category. In an article recently published in Brain, a Japanese-European team of scientists, including researchers from Fujita Health University, describe mutations in the LIG3 gene, which plays a crucial role in mitochondrial DNA replication. These mutations […]
Pandemic drinking puts more than 100 people in hospital with worst affected patients in their early 60s or early 70s NHS had 750,000 alcohol-related admissions between last April and December Figures show there were almost 20,000 admissions among those aged 90-plus Drinkers in their 20s and 30s accounted for a relatively small number of cases More than […]
Multiple system atrophy (MSA) is a neurodegenerative disease with multiple debilitating symptoms. One of them is sleep disorders; however, owing to limited research, little is known about why only some patients are affected, how sleep disorders influence MSA severity, or even how sleep disorders vary across different MSA subtypes. Now researchers at West China Hospital […]
Researchers at Henry Ford Health System have found that workers in construction and other manufacturing jobs are more susceptible for developing carpal tunnel syndrome than those who work in office jobs. In a retrospective study published in the Journal of Occupational and Environmental Medicine, researchers report that manual labor jobs that require lifting, gripping and […]
In a study that looked at racial differences in outcomes of COVID-19 patients admitted to the intensive care unit, researchers at Henry Ford Hospital in Detroit found that patients of color had a lower 28-day mortality than white patients. Race, however, was not a factor in overall hospital mortality, length of stay in the ICU […]
As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age. Progressive, age-related muscle loss is called sarcopenia, and it can impair […]
Antibiotics have revolutionized the field of medicine by making it possible to treat most known microbial diseases today. However, their uncontrolled usage has led to the major global problem of antibiotic resistance. As we continue to exploit antibiotics, sometimes at doses much higher than needed, disease-causing bacteria are rapidly evolving defense strategies to evade them. […]
Six months after it was controversially hailed by Trump administration officials as a "breakthrough" therapy to fight the worst effects of Covid-19, convalescent plasma appears to be on the ropes. The treatment that infuses blood plasma from recovered Covid patients into people newly infected in hopes of boosting their immune response has not lived up […]
The fast-spreading UK, South Africa, and Brazil coronavirus variants are raising both concerns and questions about whether COVID-19 vaccines will protect against them. New work led by Bing Chen, PhD, at Boston Children's Hospital analyzed how the structure of the coronavirus spike proteins changes with the D614G mutation — carried by all three variants — […]
In the year since the World Health Organization declared a global pandemic, millions of families have endured the excruciating rise and fall of the U.S. outbreak — waves of sickness that leave untold wounds long after hospitalizations ebb and infections subside. Some have borne the tragedy more than others, with multiple family members lost to […]