Researchers at the Technion—Israel Institute of Technology have developed an innovative treatment for breast cancer, based on analgesic nanoparticles that target the nervous system. The study, published in Science Advances, was led by Professor Avi Schroeder and Ph.D. student Maya Kaduri of the Wolfson Faculty of Chemical Engineering. Breast cancer is one of the most […]
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Killer T cells could be recruited to ignite immune response against cancer
A University of Alberta researcher has discovered how two signaling molecules recruit immune cells known as “killer” T cells to a specific type of colon cancer with more favorable patient outcomes. The finding may represent a therapeutic strategy to target other types of cancers. Kristi Baker, assistant professor in the Department of Oncology, examined tumors […]
Antibody-producing b cells may be ‘predestined’ for their fates
The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise. The study, published Sept. 23 in Nature Immunology, combined […]
Using Microorganisms to Treat Cancer
Approaches to treating cancer are as varied and numerous as cancers themselves, ranging from the more common surgical, chemotherapeutic, and radiotherapeutic strategies to more recently developed immunotherapeutic and gene-editing approaches. Thanks to recent advancements in our ability to edit the genome, some research groups are working towards creating therapeutic bacteria with applications in a wide […]
Non-neuronal cells drive sex differences in early brain development
During development, brain cells may find different ways to connect with each other based on sex, according to researchers at the Marshall University Joan C. Edwards School of Medicine. The study, recently published in eNeuro, an open access journal for the Society of Neuroscience, showed a significantly more robust synaptogenic response in male-derived cells compared […]
Like priming a pump, cells damaged by chronic lung disease can result in severe COVID
The results of a study by an international scientific team co-led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that—like pouring water atop a wellhead before pumping—the airway cells of patients with chronic lung diseases are “primed” for infection by the COVID-19 virus, resulting in more severe symptoms, poorer […]
Genes and immune cells predict immunotherapy success in bladder cancer
Sets of genes associated with resistance to immunotherapy in patients with metastatic urothelial cancer of the bladder have been identified and validated by researchers at Mount Sinai. In a study published in Clinical Cancer Research, the team uncovered gene signatures representing adaptive immunity and pro-tumorigenic inflammation that were responsible for sensitivity or resistance to immune […]
Medical cannabis can reduce essential tremor by turning on overlooked cells in central nervous system
Medical cannabis is a subject of much debate. There is still a lot we do not know about cannabis, but researchers from the Department of Neuroscience at the Faculty of Health and Medical Sciences have made a new discovery that may prove vital to future research into and treatment with medical cannabis. Cannabinoids are compounds […]
Stem cells derived from fat show promise as a treatment for mass radiation exposure
Nuclear power offers an efficient, reliable way to provide energy to large populations—as long as all goes well. Accidents involving nuclear reactors such as those that took place in 1986 at Chernobyl and at Fukushima Daiichi after the March 2011 tsunami raise major concerns about what happens if the worst occurs and large numbers of […]
Researchers discover new pathway for attacking cancer cells
When treating cancer, researchers are always searching for ways to remove cancer cells while minimizing damage to the rest of the body. One possible approach is to find processes unique to cancer cells, and which would allow specific targeting. If such a process can be disrupted, only those cells would be affected. A process (or […]