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Centrioles are cylindrical structures involved in the generation of microtubules-;fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes. In addition, centriole are required to build cilia, hair-like extensions on the cell surface that allow cells to receive and respond to signals from the outside. […]
By studying a disease caused by a close cousin of the virus behind COVID-19, a team of scientists has identified a compound that shows potential in easing the symptoms of coronavirus infections. The team, from the Department of Energy's Pacific Northwest National Laboratory and the University of North Carolina at Chapel Hill, studied the virus […]
Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube. Now, for the first time, a USC-led study in Nature Communications describes how stem cells […]
Mesenchymal stem cells (MSCs) are thought to have great potential in the field of regenerative medicine, which has the aim of restoring damaged tissues. However, not much was known about in vivo plasticity of them—until now. Researchers have identified a subpopulation of MSCs that promote the healing of bone fractures and show an enhanced ability […]
The emergence of the severe acute respiratory syndrome coronavirus (SARS-CoV-2) in December 2019 was followed by its rapid worldwide spread, causing the coronavirus disease 2019 (COVID-19) to become a public health emergency and then be declared a pandemic by the World Health Organization in March 2020. Study: An iTSC-derived placental model of SARS-CoV-2 infection reveals […]
A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study. The research found the cell-based quadrivalent influenza vaccine (QIVc) produced a sufficient immune response in children aged two to 18 years. The lead investigator on the study was Professor Terry Nolan, head of the Vaccine […]
The emergence of genetically diverse severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, with altered phenotypic properties, has occurred due to the continuous mutation of the original strain first reported in Wuhan, China, in 2019. In 2021, the World Health Organization categorized these variants as variants of concern (VOC) and variants of interest (VOI) based […]
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear. Published in the journal Nature Communications, a study […]
A team of international scientists and clinical experts have unraveled a new cell type in human skin that contributes to inflammatory skin diseases such as atopic dermatitis (AD) and psoriasis (PSO). Their study findings were published in the Journal of Experimental Medicine in September 2021. The team hails from A*STAR's Singapore Immunology Network (SIgN), in […]
DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit of a helix containing what are known as "DNA bases". Maintenance of DNA is extremely important for smooth operation of all bodily functions. […]