Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today. The findings, published in Science Translational Medicine, raise hopes that new treatment options could one-day be developed for DMD, an uncurable genetic condition characterized by progressive muscle degeneration. About 1 in […]
Home »
Antifungal and antidepressant drugs may help protect against COVID-19
New research published in the British Journal of Pharmacology indicates that two currently available medications—an antifungal drug and an antidepressant—can effectively inhibit the virus that causes COVID-19 in laboratory cells. Investigators found that the antifungal itraconazole and the antidepressant fluoxetine each blocked the production of infectious SARS-CoV-2 virus in cell culture lab tests. When either […]
Novavax COVID-19 vaccine shows 96.4% efficacy, less protection against variants
Fox News Flash top headlines for March 12 Fox News Flash top headlines are here. Check out what’s clicking on Foxnews.com. The Maryland-based biotech Novavax has announced its COVID-19 vaccine candidate has 96.4% efficacy against COVID-19 illness from the original strain, sliding to 86.3% against the U.K. variant and falling to 48.6% in South Africa amid circulation […]
Why the lovable llama might be a secret weapon against COVID-19
As the fight against COVID-19 continues, scientists have turned to an unlikely source for a potentially effective treatment: tiny antibodies naturally generated by llamas. While the world has welcomed the news of multiple vaccines against COVID-19, the search for effective treatments for those who contract the virus is ongoing. Now scientists are looking to what […]
Phase 1 clinical trial of a monoclonal antibody against the chikungunya virus
Evotec, a drug company headquartered in Hamburg, Germany, has begun a phase 1 clinical trial of a monoclonal antibody against the chikungunya virus that was identified at Vanderbilt University Medical Center. This is the second monoclonal antibody against the debilitating tropical viral infection isolated in the lab of James Crowe Jr., MD, director of the […]
New evidence COVID-19 antibodies, vaccines less effective against variants
New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic. With few exceptions, whether such antibodies were produced in response to vaccination or natural infection, or […]
Monoclonal antibodies against MERS coronavirus show promise in phase 1 trial
A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes Middle East respiratory syndrome (MERS) found that they were well tolerated and generally safe when administered simultaneously to healthy adults. The experimental mAbs, REGN3048 and REGN3051, target the MERS coronavirus (MERS CoV) spike protein used by the […]
Cambodia begins vaccination campaign against COVID-19
Three sons of Cambodian leader Hun Sen were inoculated against COVID-19 on Wednesday as the country began distributing vaccines donated from its closest ally, China. Hun Manet, the head of the army and Hun Sen’s eldest son, urged all Cambodians to be vaccinated and thanked China for the donation. “I trust this vaccine and that […]
Brain protein that causes Alzheimer’s also protects against the disease
Findings from a new study on Alzheimer’s disease (AD), led by researchers at the University of Saskatchewan (USask), could eventually help clinicians identify people at highest risk for developing the irreversible, progressive brain disorder and pave the way for treatments that slow or prevent its onset. The research, published in the journal Scientific Reports in […]
Novel antiviral drug significantly more potent against SARS-CoV-2
The antiviral drug plitidepsin is between 10 and 100 times more effective against SARS-CoV-2, including the new UK variant, than the NHS approved drug remdesivir, finds new preclinical research involving UCL scientists. As part of a coronavirus collaboration with US researchers, a UCL team was asked to test the efficacy of the drug plitidepsin on […]