Obesity is soon medically treatable?
A newly discovered Protein called BAM15 prevents weight gain and fat deposits and also decreases the blood sugar. The Protein ensures that the cell’s power plants operate less efficiently, causing you to need more energy than usual. Consequently, the more calories your body burns him to the ground state.
Researchers from the Pennington Biomedical Research Center published the first evidence that a Protein called BAM15 could be used as a drug against obesity or Obesity. The Protein decides the action of all the other known pharmacological strategies that are used in the treatment of obesity. The results of the study were recently presented in the journal “EMBO Molecular Medicine”.
Obesity is a worldwide growing Problem
Obesity affects worldwide more than 650 million people. The strong Overweight States is the main trigger for a series of dangerous health, including type 2 Diabetes, heart disease, and more than a dozen cancer types. “Nevertheless, only a handful of drugs for the treatment of fat are currently obesity approved,” says Dr. John Kirwan from the research team. Add to this that people taking these drugs rarely achieve long-term weight loss.
New ways to lose weight find
The Protein BAM15 is different from all existing drugs to weight regulation. Most of the available drugs work by reducing the appetite of the target person, whereby the persons Concerned to take in fewer calories. BAM15 followed a completely different approach. The Protein makes the power plants of the cells, the mitochondria, less efficient, causing you to burn more energy to achieve the same result.
BAM15 mice made immune to weight gain
In the new study, the scientists show scientists that mice who have been administered BAM15 against weight gain were resistant, because they consumed more calories than conspecifics that were not treated with the Protein. In addition, the blood sugar and the insulin levels of the mice by BAM15 – lowered regardless of the weight loss.
BAM15 improves insulin sensitivity
The researchers also found that BAM15 improved the insulin sensitivity of the skeletal muscles, i.e. those muscles which are the active movements of the body responsible. The insulin resistance of the skeletal muscles is a primary risk factor for the development of type-2 Diabetes, underline the researchers.
Reduction of fat accumulations
In addition, the research team was able to observe a reduction in fat accumulation in the mice, especially the fat deposits in the liver, the kidneys in the blood. This kind of fat deposits are mainly involved in the development of heart disease.
Numerous Application Possibilities
The research team believes that the Protein BAM15 new treatment options for a whole range of health problems. In addition to obesity, the Protein could also be used for the treatment of Diabetes, fatty liver and in some forms of cancer. Previously, it has to be tested extensively in humans. (vb)