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Radiomic Signature May Predict Survival in Pembro-Treated Melanoma

NEW YORK (Reuters Health) – In patients with advanced melanoma treated with pembrolizumab monotherapy, a radiomic signature derived from baseline computed tomography (CT) images may predict overall survival (OS), researchers suggest. There is a “critical need” for early radiographic markers for metastatic melanoma treated with immune checkpoint inhibitors such as pembrolizumab, because of atypical responses […]

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Uncontrolled blood pressure is sending more people to the hospital

The number of people hospitalized for a hypertensive crisis—when blood pressure increases so much it can cause a heart attack, stroke or other sudden cardiovascular event—more than doubled from 2002 to 2014, according to Cedars-Sinai investigators. The increase occurred during a period when some studies reported overall progress in blood pressure control and a decline […]

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American College of Gastroenterology issues guidelines for managing acute-on-chronic liver failure

(HealthDay)—In clinical guidelines issued by the American College of Gastroenterology and published online Jan. 10 in the American Journal of Gastroenterology, recommendations are presented for the management of acute-on-chronic liver failure (ACLF). Jasmohan S. Bajaj, M.D., from Virginia Commonwealth University in Richmond, and colleagues examined the preferred approach to management of patients with ACLF, defined […]